Location : Redwood City
Company Overview :
ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases. With a highly experienced team of experts in immunology and drug development, we are pioneering innovative approaches to target and modulate key molecular pathways that regulate the immune response.
At ImmunEdge, we are driven by a shared commitment to improving human health through innovative science. We are building a culture based on collaboration and a deep passion for advancing science. As an early joiner to the company, you will help build and cultivate an environment where every team member is encouraged to challenge ideas, think critically, and contribute their unique perspectives. We value openness, transparency, and continuous learning, and want to empower our employees to take ownership of their work while fostering a sense of community and teamwork.
Join us in shaping the future of biotechnology. Together, we can change lives.
Position :
We seek a highly skilled and motivated Senior Scientist to join our antibody discovery and protein engineering team. This individual will play a key role in the design, development, and optimization of novel antibody therapeutics, supporting early-stage discovery efforts and contributing to the advancement of candidates into development. The ideal candidate will have strong expertise in antibody discovery technologies, molecular biology, and protein engineering. This is a lab-focused role requiring deep technical expertise and scientific creativity.
Key Responsibilities :
Design, clone, and express monoclonal, bi- and multi-specific antibodies for characterization, optimization, and functional screening.
Engineer antibodies for enhanced functionality (e.g., Fc engineering, bispecifics, affinity maturation, humanization).
Design and execute high-throughput screening assays (binding, kinetics, epitope binning, cell-based functional assays).
Investigate signal transduction by phosphorylation, gene regulation, cell differentiation and proliferation, and flow cytometry.
Analyze protein structure for functional optimization and apply computational tools to accelerate discovery.
Troubleshoot experiments, analyze complex data, and propose innovative solutions.
Stay current with emerging technologies and trends in antibody discovery and protein engineering to help drive innovation.
Qualifications :
PhD in Molecular Biology, Biochemistry, Structural Biology, Immunology, or a related field with 5+ years industry experience in antibody discovery and protein engineering.
Proven hands-on experience with antibody generation platforms (e.g., display technologies, hybridoma, B-cell cloning).
Strong molecular biology skills, including cloning, vector design, and construct optimization.
Expertise in protein expression (mammalian and/or bacterial), purification, and biophysical analysis.
Familiarity with structure analysis and computational tools for antibody modeling, sequence analysis, and developability prediction is a plus.
Excellent problem-solving skills, attention to detail, and ability to manage multiple projects in a fast-paced environment.
Expected Salary Range : $142,000 - $158,000
We encourage candidates of all levels to apply as there at times is flexibility on job level and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity, and location.
ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401k plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan.
At ImmunEdge, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. ImmunEdge will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws.
Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.
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